Pregnancy hypertension

Description

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Data source
FinnGen phenocode O15_HYPTENSPREG
Hospital Discharge registry ICD-10: O14/O15/O10/O11/O13/O16, ICD-9: 642, ICD-8: 63701|63703|63704|63709|63710|63799
Cause of Death registry ICD-10: O13/O14/O15/O16/O11/O10, ICD-9: 642, ICD-8: 63701|63703|63704|63709|63710|63799
Sex specific endpoint 2
Level in the ICD-hierarchy C
First defined in version DF3
Ontology
DOID 10591
GWAS catalog 0000668
MESH D046110
SNOMED CT 398254007

Key figures

Sex All Female Male
Number of individuals 6120 6120 -
Unadjusted prevalence (%) 3.51 6.17 -
Mean age at first event (years) 29.56 29.56 -
Case fatality at 5-years (%) 0.0 0.0 -

Heritability

SNP-h2 liability CI
0.07 [0.02, 0.13]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 -
Recurrence at 6 months (%) 8.81 8.81 -

Associations

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