Otherdisorders of bone

Description

secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)

Data source
FinnGen phenocode M13_OTHERBONE
Hospital Discharge registry ICD-10: M93/M91/M89/M92/M94
Cause of Death registry ICD-10: M89/M92/M93/M91/M94
Include M13_ALGONEURO, M13_EPIPHYARR, M13_BONEDEV, M13_BONEHYPERTRPH, M13_HYPERTRPHOSTEOARTHR, M13_OSTEOLYSIS, M13_OSTEOPATHYPOSTPOLIO, M13_BONEDISNAS, M13_OSTEOPATHYINOTH, M13_CHRONDROPATHIES
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 10393
GWAS catalog 1001174
MESH D001847
SNOMED CT 203357004

Key figures

Sex All Female Male
Number of individuals 2682 1518 1164
Unadjusted prevalence (%) 1.54 1.53 1.55
Mean age at first event (years) 38.57 40.35 36.26
Case fatality at 5-years (%) 1.38 1.19 1.63

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 23.71 26.02 20.7

Associations

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