Osteoporosis

Description

osteoporosis: A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).

Data source
FinnGen phenocode M13_OSTEOPOROSIS
Hospital Discharge registry ICD-10: M81/M80, ICD-8: 7230|72391
Cause of Death registry ICD-10: M80/M81, ICD-8: 7230|72391
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 11476
GWAS catalog 0003882
MESH D010024
SNOMED CT 64859006

Key figures

Sex All Female Male
Number of individuals 2452 1942 510
Unadjusted prevalence (%) 1.41 1.96 0.68
Mean age at first event (years) 65.59 66.74 61.23
Case fatality at 5-years (%) 11.62 11.23 13.14

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 2
Recurrence at 6 months (%) 34.31 33.08 39.02

Associations

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