Gastro-oesophageal reflux disease

Description

gastroesophageal reflux disease: A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa.

Data source
FinnGen phenocode K11_REFLUX
Hospital Discharge registry ICD-10: K21, ICD-9: 5301A
Cause of Death registry ICD-10: K21, ICD-9: 5301A
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 8534
GWAS catalog 0003948
MESH D005764
SNOMED CT 235595009

Key figures

Sex All Female Male
Number of individuals 10167 5902 4265
Unadjusted prevalence (%) 5.83 5.95 5.68
Mean age at first event (years) 54.26 54.01 54.61
Case fatality at 5-years (%) 2.56 1.63 3.85

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 24.08 23.65 24.67

Associations

Loading associations…