Fibrosis and chirrhosis of liver

Description

cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.

Data source
FinnGen phenocode K11_FIBROCHIRLIV
Hospital Discharge registry ICD-10: K74, ICD-8: 5719
Cause of Death registry ICD-10: K74, ICD-8: 5719
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 5082
GWAS catalog 0001422
MESH D008103
SNOMED CT 19943007

Key figures

Sex All Female Male
Number of individuals 569 309 260
Unadjusted prevalence (%) 0.33 0.31 0.35
Mean age at first event (years) 58.54 57.68 59.56
Case fatality at 5-years (%) 18.28 10.03 28.08

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 4 1
Recurrence at 6 months (%) 55.36 68.28 40.0

Associations

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