Noninfective enteritis and colitis

Description

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Data source
FinnGen phenocode K11_ENERCOLNONINF
Hospital Discharge registry ICD-10: K50/K52/K51
Cause of Death registry ICD-10: K52/K50/K51
Include K11_CROHN, K11_ULCER, K11_KELAIBD, K11_OTHENTERCOL
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 8577
GWAS catalog 0000729
MESH D005759
SNOMED CT 64766004

Key figures

Sex All Female Male
Number of individuals 6513 3716 2797
Unadjusted prevalence (%) 3.74 3.75 3.72
Mean age at first event (years) 44.3 44.03 44.66
Case fatality at 5-years (%) 3.24 2.96 3.61

Heritability

SNP-h2 liability CI
0.05 [0.0, 0.1]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 3
Recurrence at 6 months (%) 52.54 51.72 53.63

Associations

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