Cholangitis (primary sclerosing, PSC), with reimbursement 202

Description

sclerosing cholangitis: A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

Data source
FinnGen phenocode K11_CHOLANGI_STRICT
Hospital Discharge registry ICD-10: K830, ICD-8: 5750[4-5]
Cause of Death registry ICD-10: K830, ICD-8: 5750[4-5]
Conditions required K11_REIMB_202
First defined in version DF3
Ontology
DOID 14268
GWAS catalog 0004268
MESH D001660
SNOMED CT 235917005

Key figures

Sex All Female Male
Number of individuals 158 94 64
Unadjusted prevalence (%) 0.09 0.09 0.09
Mean age at first event (years) 44.55 46.56 41.59
Case fatality at 5-years (%) 2.53 3.19 1.56

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 39.37 38.49 40.31

Associations

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