Rheumatic fever without mention of heart involvement

Description

rheumatic fever: Rheumatic fever (RF) is a multisystem inflammatory disease occurring as a post-infectious, nonsuppurative sequela of untreated streptococcus pyogenes (Group A streptococcus [GAS]) pharyngitis, and mainly occurs in individuals aged 5 to 15 years. The most common presenting signs are fever, migratory polyarthritis and carditis.

Data source
FinnGen phenocode I9_RHEUFEVWITHOUTHEART
Hospital Discharge registry ICD-10: I029/I00, ICD-9: 390, ICD-8: 390
Cause of Death registry ICD-10: I00/I029, ICD-9: 390, ICD-8: 390
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 1586
GWAS catalog 1001160
MESH D012213
SNOMED CT 58718002

Key figures

Sex All Female Male
Number of individuals 44 22 22
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 32.96 29.15 36.77
Case fatality at 5-years (%) 6.82 9.09 4.55

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 9.09 9.09 9.09

Associations

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