Disorders of the thyroid gland

Description

thyroid nodule: A small circumscribed mass in the THYROID GLAND that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (GOITER, NODULAR).

Data source
FinnGen phenocode E4_THYROID
Include E4_CONGEIOD, E4_IODGOITRE, E4_IODTHYR, E4_IODHYPSUB, E4_HYTHYSUBS, E4_HYTHYPOSTINF, E4_ATROTHY, E4_MYXOCO, E4_HYTHYNAS, E4_GOITREDIFF, E4_GOITRENOD, E4_GOITREMULTINOD, E4_GOITRENAS, E4_THYTOXGOITDIF, E4_THYTOXECT, E4_THYCRISIS, E4_THYTOXNAS, E4_THYROIDITACU, E4_THYROIDITSUBAC, E4_THYROIDITCHRON, E4_THYROIDITAUTOIM, E4_THYROIDITDRUG, E4_THYROIDITNAS, E4_HYPERSECCAL, E4_GOITREDYS, E4_THYROIDNASOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 14313
GWAS catalog 1001436
MESH D013959

Key figures

Sex All Female Male
Number of individuals 24137 19487 4650
Unadjusted prevalence (%) 13.85 19.65 6.19
Mean age at first event (years) 51.59 50.55 55.96
Case fatality at 5-years (%) 1.64 1.17 3.63

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 21 22 16
Recurrence at 6 months (%) 86.0 86.61 83.52

Associations

Loading associations…