Type 1 diabetes with ophthalmic complications

Description

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Data source
FinnGen phenocode E4_DM1OPTH
Hospital Discharge registry ICD-9: 2504B
Cause of Death registry ICD-9: 2504B
Level in the ICD-hierarchy 4
First defined in version DF3
Ontology
DOID 8947
GWAS catalog 0003770
MESH D003930
SNOMED CT 4855003

Key figures

Sex All Female Male
Number of individuals 2339 1194 1145
Unadjusted prevalence (%) 1.34 1.2 1.52
Mean age at first event (years) 35.73 34.61 36.9
Case fatality at 5-years (%) 2.39 1.76 3.06

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 6 7 6
Recurrence at 6 months (%) 70.84 72.45 69.17

Associations

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