Other disorders of white blood cells
Description
Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.
Data source
| FinnGen phenocode | D3_OTHERWHITECELL |
| Hospital Discharge registry | ICD-10: D72 |
| Cause of Death registry | ICD-10: D72 |
| Include | D3_LEUKOANOMALIAGEN, D3_EOSINOPHILIA, D3_WHITEBLOODCELLNAS |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 501 | 272 | 229 |
| Unadjusted prevalence (%) | 0.29 | 0.27 | 0.3 |
| Mean age at first event (years) | 53.33 | 51.74 | 55.23 |
| Case fatality at 5-years (%) | 5.79 | 3.68 | 8.3 |
Longitudinal metrics
| Sex | All | Female | Male |
| Median nb. of events per indiv. | 1 | 1 | 1 |
| Recurrence at 6 months (%) | 27.74 | 29.04 | 26.2 |
Associations
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