Non-allergic asthma

Description

asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Data source
FinnGen phenocode ASTHMA_NONALLERG
Conditions required !(L12_ATOPIC|ALLERG_RHINITIS|H7_ALLERGICCONJUNCTIVITIS|FOOD_ALLERGY|Z21_DESEN_ALLERGE|POLLENALLERG)
Include NONALLERG_ASTHMA
First defined in version DF2
Ontology
DOID 2841
GWAS catalog 0000270
MESH D001249
SNOMED CT 31387002

Key figures

Sex All Female Male
Number of individuals 2464 1438 1026
Unadjusted prevalence (%) 1.41 1.45 1.37
Mean age at first event (years) 52.03 51.17 53.24
Case fatality at 5-years (%) 4.75 3.27 6.82

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 3 3
Recurrence at 6 months (%) 67.77 68.7 66.31

Associations

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